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ea0063p1063 | Pituitary and Neuroendocrinology 3 | ECE2019

Cumulative GH exposure as risk factor for mortality and morbidity in patients with acromegaly

Galoiu Simona , Silea Simona , Mailat Monica , Baciu Ionela , Trifanescu Raluca Alexandra , Niculescu Dan Alexandru , Capatina Cristina , Radian Serban , Baculescu Nicoleta , Caragheoorgheopol Andra , Dumitrascu Anda , Poiana Catalina

Background: In patients with acromegaly, mortality depends most on achievement of control of GH/IGF1 levels. However, some of the complications of acromegaly still develop, despite successful control of disease. The aim of the study is to correlate mortality and morbidity with cumulative GH exposure in these patients compared to last GH/IGF1 level.Methods: We studied retrospectively 336 patients with acromegaly consecutively evaluated at least twice duri...

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Cumulative GH exposure as risk factor for mortality and morbidity in patients with acromegaly

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